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Dysbiosis (characterized by reduced microbial diversity and increased pathogen abundance) may facilitate toxin production, wherein these toxinsthrough induction of cytotoxicity, endothelial dysfunction, oxidative stress, inflammation, and fibrosisdrive an immune-centric vicious cycle, thereby exacerbating cardiovascular complications

A salt-form theory may be chemically plausible

The benzyl alcohol inhibits bacterial growth, which means that a reconstituted vial can, in principle, be used across multiple doses over a period of days to weeks rather than being discarded after a single use as would be required with plain sterile water

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